PrEP (Pre-exposure prophylaxis) refers to a dedicated HIV prevention method utilized by individuals who are at a higher risk of acquiring the infection. By taking a daily or on-demand dosage of PrEP drugs, persons exposed to the virus can significantly decrease their risk of getting infected. In this article, we will explore several options available for PrEP.
To begin, the most common PrEP option is a combination of Tenofovir and Emtricitabine. Marketed under the brand name Truvada or its generic versions, this medication is approved for use by individuals who are HIV negative and have a substantial risk of contracting the infection. It involves taking a single PrEP pill every day. Studies have shown that when taken consistently, Truvada can reduce the risk of getting HIV from sex by about 99%.
Another option is the Descovy for PrEP. Just like Truvada, Descovy is a combination of two drugs - Emtricitabine and Tenofovir alafenamide. However, Descovy is generally not recommended for individuals who engage in receptive vaginal sex since the efficacy of this drug for such situations is not well-studied. On the positive side, Descovy has been indicated to have fewer bone and kidney side effects compared to Truvada, making it a suited option for those at risk of these side effects.
The newest form of PrEP is Cabotegravir, which is an injectable option. The long-acting injectable form of PrEP, called Apretude, is administered once every two months and is meant to be used by adults and adolescents who weigh at least 35 kilograms and are at risk of getting HIV through sex. This option eliminates the need for a daily pill and offers consistent protection from infection within its eight-week duration.
On-demand or event-based PrEP, another method, involves taking the medication only in the days surrounding sexual activity. More common in Europe, this method requires taking two pills of Truvada 2-24 hours before sex, followed by one pill each day until two days after the last sexual exposure. On-demand PrEP might be a fit for individuals with less frequent sexual activity or those who find it hard to take a pill every single day.
Each PrEP option holds its unique benefits and potential drawbacks. Deciding on the most suitable PrEP regimen involves an open discussion with healthcare providers considering factors such as lifestyle, medical history, and anticipated compliance to the intake regimen.
As every person's scenario is unique, the process of choosing the correct option requires a tailored approach. Healthcare providers should be consulted to discuss side effects, cost, interaction with other medication, and effectiveness regarding one's specific situation. Remember, along with PrEP use, combining other prevention methods like regular HIV testing and condom usage maximizes protection against HIV.