Major depression, also referred to as clinical depression, is a mental disorder that affects millions of people around the world. Depression is more than just feeling sad or having the "blues". It is a persistent feeling of sadness and hopelessness that can impact a person's ability to function in daily life. Here are some of the most common symptoms of major depression:

1. Persistent sadness or feelings of hopelessness

People with major depression often experience a persistent feeling of sadness or a sense of emptiness that does not go away, even when there is no logical reason for it. They may feel helpless or hopeless and be unable to picture a happier future for themselves.

2. Loss of interest in activities

People with major depression may lose interest in activities that they once enjoyed, such as hobbies, socializing, or spending time with friends and family. They may struggle to find pleasure in anything, even activities that they used to find fun.

3. Fatigue or loss of energy

Depression can cause a significant decrease in energy levels, making it difficult for people to carry out even simple tasks. They may feel constantly tired or find themselves sleeping for extended periods throughout the day.

4. Insomnia or oversleeping

Some people with major depression may experience insomnia or difficulty sleeping. Others may find that they can't seem to get enough sleep and feel the need to sleep excessively throughout the day.

5. Changes in appetite or weight

Depression may result in a change in appetite, which can lead people to gain or lose weight. This may be due to a lack of desire to eat, or a need to comfort eat to cope with feelings of sadness.

6. Decreased concentration or memory problems

Depression can affect a person's ability to concentrate or remember things. They may find it difficult to pay attention, complete tasks or remember appointments.

7. Irritability, anger, or restlessness

People with depression may experience irritability or restlessness, which can cause them to feel tense or easily angered. This may be exacerbated by feelings of hopelessness or loss of control.

8. Physical symptoms

Depression can also cause a range of physical symptoms, including dizziness, headaches, body aches, and stomach problems. These symptoms may not have a physical cause but are instead a manifestation of the person's mental state.

In conclusion, anyone experiencing any of these symptoms should seek medical help from a professional. Treatment options such as medication, psychotherapy, or a combination of the two can be highly effective in managing depression and improving overall quality of life.