Myasthenia gravis (MG) is a chronic, progressive autoimmune neuromuscular disorder. This means that the body’s immune system attacks its own nerve cells, leading to muscle weakness, especially in the eyelids, arms, and legs. It is estimated to affect between 50,000 – 100,000 people in the United States.
MG occurs when the body forms antibodies which attack the nerve endings that send signals from the brain to the muscles. As a result, the muscles’ ability to contract is impaired. This can lead to symptoms such as double vision, facial droopiness, difficulty in swallowing, difficulty in breathing, and weakness in the arms and legs. The weakness can range from mild to severe, and can even cause difficulty in speaking and walking.
MG is usually treated with a combination of medications, lifestyle changes, and physical and occupational therapy. Medications such as acetylcholinesterase inhibitors, which improve communication between the nerves and muscles, are commonly used. Additionally, steroids can help reduce inflammation, and newer treatments such as monoclonal antibodies and immune suppressants may help to reduce inflammation and the production of antibodies.
Lifestyle changes that can help to manage MG include getting more rest, avoiding stress and caffeine, eating a balanced diet, avoiding overexertion, and doing regular exercises that are tailored to the individual’s needs. Finally, physical and occupational therapy can help to strengthen muscles, improve posture and coordination, and increase overall mobility.
Despite recent advances in treatment, symptoms of MG can still be difficult to manage. It is an incurable condition, and although it can be controlled, it can also become more severe over time. Therefore, people living with MG must learn to monitor their own symptoms and be aware of potential triggers that may cause the condition to worsen.
For those living with this condition, there are many support groups available, both in person and online, which provide resources and a sense of community. It is important to remember that people with this condition can still live full and active lives with the right interventions, support, and self-care.